Induced neuronal cells: how to make and define a neuron.
Cell Stem Cell
; 9(6): 517-25, 2011 Dec 02.
Article
em En
| MEDLINE
| ID: mdl-22136927
Cellular plasticity is a major focus of investigation in developmental biology. The recent discovery that induced neuronal (iN) cells can be generated from mouse and human fibroblasts by expression of defined transcription factors suggested that cell fate plasticity is much wider than previously anticipated. In this review, we summarize the most recent developments in this nascent field and suggest criteria to help define and categorize iN cells that take into account the complexity of neuronal identity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Diferenciação Celular
/
Neurônios
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Cell Stem Cell
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos