Successful treatment of aciclovir and foscarnet resistant Herpes simplex virus lesions with topical imiquimod in patients infected with human immunodeficiency virus type 1.
J Med Virol
; 84(2): 194-7, 2012 Feb.
Article
em En
| MEDLINE
| ID: mdl-22170537
ABSTRACT
Aciclovir (ACV)-resistant Herpes simplex virus type-2 (HSV-2) infections are observed commonly in patients also infected with HIV-1. The use of foscarnet (FOS) in these patients may also lead to resistance. This situation can become a difficult therapeutic challenge. Four cases of patients infected with HIV and with mucocutaneous HSV-2 resistant to ACV and FOS are reported. These patients were treated successfully with topical 5% imiquimod. Imiquimod treatment also appeared to delay the time to recurrence of HSV lesions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Simplexvirus
/
Aminoquinolinas
/
Herpes Simples
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Med Virol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
França