Distinct neural networks underlie encoding of categorical versus coordinate spatial relations during active navigation.
Neuroimage
; 60(3): 1630-7, 2012 Apr 15.
Article
em En
| MEDLINE
| ID: mdl-22300811
ABSTRACT
It has been proposed that spatial relations are encoded either categorically, such that the relative positions of objects are defined in prepositional terms; or in terms of visual coordinates, such that the precise distances between objects are represented. In humans, it has been assumed that a left hemisphere neural network subserves categorical representations, and that coordinate representations are right lateralised. However, evidence in support of this distinction has been garnered exclusively from tasks that involved static, two-dimensional (2D) arrays. We used functional magnetic resonance imaging (fMRI) to identify neural circuits underlying categorical and coordinate representations during active spatial navigation. Activity in the categorical condition was significantly greater in the parietal cortex, whereas the coordinate condition revealed greater activity in medial temporal cortex and dorsal striatum. In addition, activity in the categorical condition was greater in parietal cortex within the left hemisphere than within the right. Our findings are consistent with analogous studies in rodents, and support the suggestion of distinct neural circuits underlying categorical and coordinate representations during active spatial navigation. The findings also support the claim of a left hemispheric preponderance for the processing of categorical spatial relations.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Orientação
/
Percepção Espacial
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Tomada de Decisões
/
Movimento
/
Rede Nervosa
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Neuroimage
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Austrália