Invasive aspergillosis in a putty-nosed monkey (Cercopithecus nictitans) with adrenocortical Cushing's syndrome.
J Med Primatol
; 41(3): 172-5, 2012 Jun.
Article
em En
| MEDLINE
| ID: mdl-22429114
ABSTRACT
BACKGROUND:
An 18-year-old captive female putty-nosed-monkey (Cercopithecus nictitans) with a history of long-term infertility and hyperglucocorticism was euthanized because of perforating thoracic trauma induced by group members and subsequent development of neurological signs.METHODS:
Complete necropsy and histopathological examination of formalin-fixed tissue samples was carried out.RESULTS:
The monkey showed invasive pulmonary and cerebral infection with Aspergillus fumigatus together with adrenocortical neoplasia and signs of Cushing's syndrome, such as alopecia with atrophic skin changes, evidence for diabetes mellitus and marked immunosuppression.CONCLUSIONS:
Spontaneous endocrinopathies are rarely described in non-human primates. Here we report the first case of spontaneous adrenocortical hyperglucocorticism predisposing to systemic aspergillosis in a putty-nosed monkey.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cercopithecus
/
Hipersecreção Hipofisária de ACTH
/
Aspergilose Pulmonar Invasiva
/
Doenças dos Macacos
Limite:
Animals
Idioma:
En
Revista:
J Med Primatol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Alemanha