Stability of vaccinia-vectored recombinant oral rabies vaccine under field conditions: a 3-year study.
Can J Vet Res
; 75(4): 278-84, 2011 Oct.
Article
em En
| MEDLINE
| ID: mdl-22468025
ABSTRACT
Rabies is an incurable zoonotic disease caused by rabies virus, a member of the rhabdovirus family. It is transmitted through the bite of an infected animal. Control methods, including oral rabies vaccination (ORV) programs, have led to a reduction in the spread and prevalence of the disease in wildlife. This study evaluated the stability of RABORAL, a recombinant vaccinia virus vaccine that is used in oral rabies vaccination programs. The vaccine was studied in various field microenvironments in order to describe its viability and facilitate effective baiting strategies. Field microenvironments influenced the stability of this vaccine in this study. This study emphasizes the importance of understanding how vaccines perform under varying field conditions in order to plan effective baiting strategies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Raiva
/
Vacínia
/
Vacina Antirrábica
/
Estabilidade de Medicamentos
/
Animais Selvagens
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
Can J Vet Res
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos