Prevalence of and racial differences in pterygium: a multiethnic population study in Asians.
Ophthalmology
; 119(8): 1509-15, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-22494631
ABSTRACT
PURPOSE:
To describe the prevalence and risk factors of pterygium in a multiethnic Asian population and to examine racial differences.DESIGN:
Population-based study in Singapore, located 1° north of the equator.PARTICIPANTS:
Data were analyzed from 8906 participants from 3 population-based studies of Malays, Indians, and Chinese persons 40 years of age and older conducted between 2004 and 2011.METHODS:
Standardized slit-lamp examinations were performed by trained study ophthalmologists to examine the anterior segment for evidence of pterygium. Every subject underwent standardized systemic and ocular examinations, interviewer-administered questionnaires, and blood investigations for risk factor assessment. Regression and principle component analysis models were constructed to study the relationship of race and other factors to pterygium. MAIN OUTCOMEMEASURES:
Any pterygium and severe (grade 3 or opaque) pterygium.RESULTS:
The overall prevalence of any pterygium was 10.1% (n = 900), of which severe pterygium was seen in 1.6% (n = 142). The prevalence of any pterygium was more common in Malays (15.5%) than Chinese (7.0%; P<0.001) or Indians (7.0%; P<0.001). Multivariate analysis revealed increasing age (P<0.001), male gender (P<0.001), Malay race (P<0.001), and having a poorer education level (P<0.001) as significant factors for any pterygium. Race contributed significantly to presence of any pterygium (41%; P<0.001) or presence in both eyes (33%; P<0.001) compared with other risk factors. Severe pterygium was associated with outdoor occupation (P = 0.02), but race was not a significant risk factor in multivariate analysis.CONCLUSIONS:
This population-based study in Asian persons of different races living in the same geographical location at the equator indicated that race is a significant risk factor for pterygium, with Malays having higher prevalence than Indians and Chinese, while controlling for other risk factors.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pterígio
/
Etnicidade
/
Povo Asiático
Tipo de estudo:
Etiology_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Ophthalmology
Ano de publicação:
2012
Tipo de documento:
Article