The usefulness of infraorbital nerve enlargement on MRI imaging in clinical diagnosis of IgG4-related orbital disease.
Jpn J Ophthalmol
; 56(4): 380-2, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-22644450
ABSTRACT
PURPOSE:
To investigate the frequency of infraorbital nerve enlargement (IONE) in orbital lymphoproliferative disorders, and to show that IONE can contribute to the clinical diagnosis of IgG4-related orbital diseases (IgG4-ROD). SUBJECTS ANDMETHODS:
71 cases in which orbital lymphoproliferative disorders were diagnosed at Okayama Medical Center and Mitoyo General Hospital from April, 2004 to March, 2011 were investigated. The male-to-female ratio was 3932, and the age range 27-87 years old (average age 64.1 years). Whenever the coronal section of the infraorbital nerve was larger than that of the optic nerve on MRI, it was defined as IONE.RESULTS:
The breakdown of the 71 cases was 45 cases of non-Hodgkin lymphoma, 16 cases of IgG4-ROD, 5 cases of reactive lymphoid hyperplasia, and 5 cases of idiopathic orbital inflammation. Of these, a total of 9 cases had IONE. The incidence of IONE was compared between the IgG4-ROD patient group and the non-IgG4-ROD patient group and was significantly higher in the IgG4-ROD patient group (p < 0.0001).CONCLUSION:
If IONE is observed in a case of orbital lymphoproliferative disorders on MRI, then it is highly possible that such a case is IgG4-ROD.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Orbitárias
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Imunoglobulina G
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Imageamento por Ressonância Magnética
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Transtornos Linfoproliferativos
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Nervo Maxilar
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Jpn J Ophthalmol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Japão