Self-assembled magnetic bead biosensor for measuring bacterial growth and antimicrobial susceptibility testing.
Small
; 8(16): 2477-82, 2012 Aug 20.
Article
em En
| MEDLINE
| ID: mdl-22674520
ABSTRACT
Bacterial antibiotic resistance is one of the major concerns of modern healthcare worldwide, and the development of rapid, growth-based, antimicrobial susceptibility tests is key for addressing it. The cover image shows a self-assembled asynchronous magnetic bead rotation (AMBR) biosensor developed for rapid detection of bacterial growth. Using the biosensors, the minimum inhibitory concentration of a clinical E. coli isolate can be measured within two hours, where currently tests take 6-24 hours. A 16-well prototype is also constructed for simple and robust observation of the self-assembled AMBR biosensors.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Técnicas Biossensoriais
/
Testes de Sensibilidade Microbiana
/
Escherichia coli
/
Magnetismo
/
Anti-Infecciosos
/
Microesferas
Idioma:
En
Revista:
Small
Assunto da revista:
ENGENHARIA BIOMEDICA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Estados Unidos