Two new oxysporone derivatives from the fermentation broth of the endophytic plant fungus Pestalotiopsis karstenii isolated from stems of Camellia sasanqua.
Molecules
; 17(7): 8554-60, 2012 Jul 17.
Article
em En
| MEDLINE
| ID: mdl-22805506
ABSTRACT
Two new oxysporone derivatives, pestalrone A (1) and pestalrone B (2), along with two known structurally related compounds 3, 4, were from the fermentation broth of the endophytic plant fungus Pestalotiopsis karstenii isolated from stems of Camellia sasanqua. Their structures and relative configurations were elucidated by extensive spectroscopic analysis and comparison of chemical shifts with related known compounds. Compound 2 exhibited significant activities agains HeLa, HepG2 and U-251 with IC50 values of 12.6, 31.7 and 5.4 µg/mL, respectively.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Camellia
/
Fungos
Limite:
Humans
Idioma:
En
Revista:
Molecules
Assunto da revista:
BIOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
China