Norepinephrine depresses the nitric oxide production in the ascidian hemocytes.
J Invertebr Pathol
; 111(2): 182-5, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-22820407
ABSTRACT
Norepinephrine (NE) is a neuro-hormone released by vertebrates and invertebrates during acute stress, and can influence their immune function. We found that NE depressed the production of nitric oxide (NO) by the hemocytes of ascidians. Our results with a fluorescent indicator for NO in assays using both NE and either α or ß-antagonist revealed that NE down-regulated NO production by the ascidian hemocytes. Our data suggest that NE may be acting via specific hemocyte receptors to induce a decrease in immune function.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Urocordados
/
Norepinefrina
/
Hemócitos
/
Óxido Nítrico
Limite:
Animals
Idioma:
En
Revista:
J Invertebr Pathol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Brasil