Hepatoprotective iridoid glycosides from the roots of Rehmannia glutinosa.
J Nat Prod
; 75(9): 1625-31, 2012 Sep 28.
Article
em En
| MEDLINE
| ID: mdl-22916954
Eleven new iridoid glycosides, rehmaglutosides A-K (1-11), together with 20 known analogues were isolated from the air-dried roots of Rehmannia glutinosa. The structures of these compounds were elucidated on the basis of spectroscopic data analysis and chemical evidence. Furthermore, in in vitro assays, compounds 3, 7, and 9-11 (10 µM) exhibited moderate hepatoprotective activities against D-galactosamine-induced HL-7702 cell damage.
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Base de dados:
MEDLINE
Assunto principal:
Hepatócitos
/
Rehmannia
/
Glicosídeos Iridoides
/
Glicosídeos
Limite:
Humans
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2012
Tipo de documento:
Article