[Impact of maternal hepatitis B surface antigen carrier status on preterm delivery in southern China].
Nan Fang Yi Ke Da Xue Xue Bao
; 32(9): 1369-72, 2012 Sep.
Article
em Zh
| MEDLINE
| ID: mdl-22985586
ABSTRACT
OBJECTIVE:
To explore the impact of maternal hepatitis B surface antigen (HBsAg) carrier status on the occurrence of preterm birth.METHODS:
We analyzed pregnancy-related complications, outcomes and fetal growth index in 188 HBsAg positive singleton pregnant women during the period of May 2009 to July 2011, with 265 HBsAg-negative women with singleton pregnancies in the same period serving as controls.RESULTS:
The HBsAg-positive pregnant women showed a significantly higher incidence of placenta praevia than the control group (2.66% vs 0%, P=0.03), and the incidence of preterm delivery (<37 weeks) was also significantly higher in HBsAg-positive group (12.23% vs 6.04%, P=0.02). The incidences of gestational hypertension, preeclampsia, gestational diabetes mellitus, abnormal glucose tolerance, premature rupture of membranes, cesarean delivery, and postpartum hemorrhage showed no significant differences between the two groups (P>0.05), nor did the fetal birth weight, height, head circumference or Apgar scores at 1, 5, and 10 min (P>0.05). Logistic regression identified HBsAg positivity, abnormal ALT, placenta praevia, and severe preeclampsia as the risk factors for preterm delivery.CONCLUSION:
HBsAg carrier status can increase the risk of preterm delivery in pregnancy, but it does not seem to affect the fetal growth.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
/
Portador Sadio
/
Nascimento Prematuro
/
Antígenos de Superfície da Hepatite B
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
Zh
Revista:
Nan Fang Yi Ke Da Xue Xue Bao
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
China