Diastereoselective synthesis of substituted dihydropyrans via an oxonium-ene cyclization reaction.
Org Biomol Chem
; 10(43): 8730-8, 2012 Nov 21.
Article
em En
| MEDLINE
| ID: mdl-23037969
ABSTRACT
Substituted dihydropyrans can be efficiently synthesized in good yields with excellent diastereoselectivity from the reaction of aldehydes or epoxides and ethyl 3-alkyl-3-hydroxy-5-methylhex-5-enoate via an oxonium-ene cyclization reaction catalyzed by trimethylsilyl trifluoromethanesulfonate (TMSOTf) under mild conditions.
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Base de dados:
MEDLINE
Assunto principal:
Piranos
Idioma:
En
Revista:
Org Biomol Chem
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Índia