Application of cell-based therapies in facial transplantation.
Ann Plast Surg
; 69(5): 575-9, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-23044753
ABSTRACT
The main purpose of cellular therapy application in face transplantation is the continuous need for the development of new strategies that would eliminate the use of toxic immunosuppressive protocols. Cellular therapy in transplantation can significantly benefit allograft survival and shorten healing time. Cells used for a therapeutic purpose are isolated mostly from bone marrow and adipose tissues. They have the ability to proliferate and differentiate in the transplanted tissue and have immunomodulatory activity. Most of the cellular therapies such as T-regulatory, dendritic, and chimeric cells are still in the experimental stage. Molecular characterization of these cells and the mechanism of their participation in allograft acceptance and rejection are not well established and will contribute to the future of modern transplantology.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transplante de Células
/
Transplante de Face
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
Ann Plast Surg
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Estados Unidos