[Clinical evaluation of periodontal intrabony defects treated with a reconstituted bovine porous bone mineral containing bone morphogenetic proteins].
Beijing Da Xue Xue Bao Yi Xue Ban
; 44(5): 797-800, 2012 Oct 18.
Article
em Zh
| MEDLINE
| ID: mdl-23073596
ABSTRACT
OBJECTIVE:
To compare the outcomes of bovine porous bone mineral (BPBM) containing bone morphogenetic proteins (BMP) and BPBM alone in periodontal intra-bony defects.METHODS:
In the study, 22 intrabony defects of 9 patients with periodontitis were recruited. All the patients had at least one pair of intrabony defects of ≥3 mm. The split-mouth and single blind methods were used. The defects were randomly assigned to BPBM containing BMP (test) or BPBM alone (control). After debridement, the intrabony defects were treated by bone graft. Assessments at baseline and after 6 months included plaque index, attachment level, probing pocket depth, bleeding indexes on probing and gingival recession. The early wound-healing, adverse effects and patients' perceptions were also recorded.RESULTS:
The gain in clinical attachment was (3.0±1.2) mm in the test group and (3.2±1.1) mm in the control group. The pocket reduction was (3.4±1.5) mm in the test group and (2.8±1.0) mm in the control group. The reduction of bleeding index was 1.9±1.3 in the test group and 2.3±0.8 in the control group. There was no statistical difference between the test group and control group (P>0.05).CONCLUSION:
Both treatment modalities led to similar significant clinical improvements.
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Base de dados:
MEDLINE
Assunto principal:
Periodontite
/
Perda do Osso Alveolar
/
Regeneração Tecidual Guiada Periodontal
/
Proteínas Morfogenéticas Ósseas
/
Minerais
Tipo de estudo:
Clinical_trials
/
Etiology_studies
Limite:
Adult
/
Animals
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Beijing Da Xue Xue Bao Yi Xue Ban
Assunto da revista:
MEDICINA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
China