The influence of midazolam on the plasma concentrations of bupivacaine and lidocaine after caudal injection of a mixture of the local anesthetics in children.
Acta Anaesthesiol Scand
; 34(1): 44-6, 1990 Jan.
Article
em En
| MEDLINE
| ID: mdl-2309541
ABSTRACT
Twenty children undergoing surgery received a caudal block using 1 ml per kg of a mixture of 50% lidocaine (1%) and 50% bupivacaine (0.25%). They were randomly allocated to two groups, one of which received midazolam 0.4 mg/kg rectally as premedication. Midazolam administration resulted in a significantly lower AUC value for lidocaine but did not influence the plasma concentrations of bupivacaine.
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Base de dados:
MEDLINE
Assunto principal:
Midazolam
/
Bupivacaína
/
Anestesia Caudal
/
Anestesia Epidural
/
Lidocaína
Tipo de estudo:
Clinical_trials
Limite:
Child
/
Child, preschool
/
Humans
/
Male
Idioma:
En
Revista:
Acta Anaesthesiol Scand
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
França