A phosphatidylcholine hyaluronic acid chitin-nanofibrils complex for a fast skin remodeling and a rejuvenating look.
Clin Cosmet Investig Dermatol
; 5: 213-20, 2012.
Article
em En
| MEDLINE
| ID: mdl-23293530
ABSTRACT
BACKGROUND:
The reduction of mortality worldwide has led older individuals to seek intervention modalities to improve their appearance and reverse signs of aging.OBJECTIVE:
We formulated a medical device as innovative block-polymer nanoparticles based on phosphatidylcholine, hyaluronan, and chitin nanofibrils entrapping amino acids, vitamins, and melatonin.METHODS:
Viability and collagen synthesis were controlled on fibroblasts ex vivo culture while adenosine triphosphate production was evaluated on keratinocytes culture. Subjective and objective evaluations were performed in vivo on selected volunteer patients.RESULTS:
In accordance with our previous studies, both the in vitro and in vivo obtained results demonstrate the efficacy of the injected block-polymer nanoparticles in reducing skin wrinkling and ameliorating the signs of aging.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Clin Cosmet Investig Dermatol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Itália