Chronic stressors and trauma: prospective influences on the course of bipolar disorder.
Psychol Med
; 43(12): 2583-92, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-23419615
ABSTRACT
BACKGROUND:
Exposure to life stress is known to adversely impact the course of bipolar disorder. Few studies have disentangled the effects of multiple types of stressors on the longitudinal course of bipolar I disorder. This study examines whether severity of chronic stressors and exposure to trauma are prospectively associated with course of illness among bipolar patients.METHOD:
One hundred and thirty-one participants diagnosed with bipolar I disorder were recruited through treatment centers, support groups and community advertisements. Severity of chronic stressors and exposure to trauma were assessed at study entry with in-person interviews using the Bedford College Life Event and Difficulty Schedule (LEDS). Course of illness was assessed by monthly interviews conducted over the course of 24 months (over 3000 assessments).RESULTS:
Trauma exposure was related to more severe interpersonal chronic stressors. Multiple regression models provided evidence that severity of overall chronic stressors predicted depressive but not manic symptoms, accounting for 7.5% of explained variance.CONCLUSIONS:
Overall chronic stressors seem to be an important determinant of depressive symptoms within bipolar disorder, highlighting the importance of studying multiple forms of life stress.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estresse Psicológico
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Transtorno Bipolar
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Depressão
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Acontecimentos que Mudam a Vida
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Psychol Med
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos