An ethanolamine-phosphate modified glycolipid in Clostridium acetobutylicum that responds to membrane stress.
Biochim Biophys Acta
; 1831(6): 1185-90, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23542061
ABSTRACT
Two phosphorus-containing glycolipids have previously been observed in Clostridium acetobutylicum. We had shown that the concentration of one of them increases in response to increased unsaturation of the membrane lipid hydrocarbon chains, suggesting a potential role in the regulation of lipid polymorphism in this organism. Mass spectrometry shows that these glycolipids are ethanolamine phosphate (Etn-P)-containing derivatives of a mono- and di-glycosyldiradylglycerol. The content of both diglycosyldiradylglycerol and the Etn-P-monoglycosyldiradylglycerol, which increases upon increased unsaturation of the membrane, also increases upon addition of octanol to the medium. Thus, it appears that the Etn-P-monoglycosyldiradylglycerol along with the diglycosyldiradylglycerol may serve to stabilize the membrane bilayer during membrane stress caused by the presence of the solvents produced during fermentation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estresse Fisiológico
/
Glicolipídeos
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Membrana Celular
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Clostridium acetobutylicum
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Etanolaminas
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Lipídeos de Membrana
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos