Salivary carriage of periodontal pathogens in generalized aggressive periodontitis families.
Int J Paediatr Dent
; 24(2): 113-21, 2014 03.
Article
em En
| MEDLINE
| ID: mdl-23647376
ABSTRACT
BACKGROUND:
Generalized aggressive periodontitis (GAP) is a multifactorial disease that shows a specific microbial profile and a familial aggregation.AIM:
This study evaluated the salivary microbial profile of families with a history of GAP and compared them with healthy families.DESIGN:
Fifteen families with parents presenting periodontal health and 15 with parents with a history of GAP were selected. Each family had a child aged 6-12 years. Stimulated saliva was collected from all subjects, and Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), and Aggregatibacter actinomycetemcomitans (Aa) amounts were determined.RESULTS:
Children of GAP families showed higher detection of Aa (90%) than children of healthy families (45%) (P < 0.05). Parents with GAP showed a Pg salivary concentration statistically higher than that of healthy parents (P < 0.05).Children of GAP families, however, exhibited similar Pg concentration than healthy children (P > 0.05). Tf amounts did not differ either in parents or in children (P > 0.05) The infection risk calculation indicates that children who have one parent who is positive for Aa have 16.3 times (95% CI 3.1-87.2) more risk of being infected with Aa (P < 0.05) than children from an Aa-negative family.CONCLUSION:
It may be concluded that children of parents with aggressive periodontitis have higher levels and higher risk of Aa infection.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Periodontite
/
Saliva
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Int J Paediatr Dent
Assunto da revista:
ODONTOLOGIA
/
PEDIATRIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Brasil