[Diffuse lipid infiltration and squamous metaplasia accompanying amyloid goiter: case report]. / Amiloid guatra eslik eden diffüz yag infiltrasyonu ve skuamöz metaplazi: olgu sunumu.
Turk Patoloji Derg
; 29(2): 146-9, 2013.
Article
em Tr
| MEDLINE
| ID: mdl-23661354
ABSTRACT
Systemic amyloidosis is one of the serious complications of Familial Mediterranean Fever (FMF). Amyloid accumulation secondary to FMF can cause pressure symptoms in thyroid gland rarely. A 17-year-old male patient with the diagnosis of FMF performed the complaints of dyspnea during his follow-up period. He has demonstrated a rapidly increasing mass localized in front of his neck within the last three months that was diagnosed as a diffuse, hyperplasic and pressuring thyroid gland. Total thyroidectomy was performed. Histopathological investigation of the material obtained aft er thyroidectomy revealed diffuse lipid infiltration in parenchyma, intense amyloid accumulation around and between the follicles that caused pressure on the follicles, and cystic areas in the tissue. Squamous metaplasia foci in cyst epithelium were detected. Upon these findings the case was diagnosed as amyloid goiter accompanied by metaplastic variations. In conclusion, it can be appropriate to take into account the possibility that metaplastic variations could accompany amyloid goiter in patients with long-term FMF.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Febre Familiar do Mediterrâneo
/
Glândula Tireoide
/
Bócio
/
Amiloidose
/
Lipídeos
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Humans
/
Male
Idioma:
Tr
Revista:
Turk Patoloji Derg
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Turquia