Left ventricular reverse remodeling after transcatheter aortic valve implantation: a cardiovascular magnetic resonance study.
J Cardiovasc Magn Reson
; 15: 39, 2013 May 21.
Article
em En
| MEDLINE
| ID: mdl-23692630
ABSTRACT
BACKGROUND:
In patients with severe aortic stenosis, left ventricular hypertrophy is associated with increased myocardial stiffness and dysfunction linked to cardiac morbidity and mortality. We aimed at systematically investigating the degree of left ventricular mass regression and changes in left ventricular function six months after transcatheter aortic valve implantation (TAVI) by cardiovascular magnetic resonance (CMR).METHODS:
Left ventricular mass indexed to body surface area (LVMi), end diastolic volume indexed to body surface area (LVEDVi), left ventricular ejection fraction (LVEF) and stroke volume (SV) were investigated by CMR before and six months after TAVI in patients with severe aortic stenosis and contraindications for surgical aortic valve replacement.RESULTS:
Twenty-sevent patients had paired CMR at baseline and at 6-month follow-up (N=27), with a mean age of 80.7±5.2 years. LVMi decreased from 84.5±25.2 g/m2 at baseline to 69.4±18.4 g/m2 at six months follow-up (P<0.001). LVEDVi (87.2±30.1 ml /m2vs 86.4±22.3 ml/m2; P=0.84), LVEF (61.5±14.5% vs 65.1±7.2%, P=0.08) and SV (89.2±22 ml vs 94.7±26.5 ml; P=0.25) did not change significantly.CONCLUSIONS:
Based on CMR, significant left ventricular reverse remodeling occurs six months after TAVI.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estenose da Valva Aórtica
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Imageamento por Ressonância Magnética
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Cateterismo Cardíaco
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Função Ventricular Esquerda
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Hipertrofia Ventricular Esquerda
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Implante de Prótese de Valva Cardíaca
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Remodelação Ventricular
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Ventrículos do Coração
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Prognostic_studies
Limite:
Aged
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Aged80
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Female
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Humans
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Male
Idioma:
En
Revista:
J Cardiovasc Magn Reson
Assunto da revista:
ANGIOLOGIA
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CARDIOLOGIA
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DIAGNOSTICO POR IMAGEM
Ano de publicação:
2013
Tipo de documento:
Article