Acute generalized exanthematous pustulosis during antituberculosis therapy.
Clin Ter
; 164(2): e137-8, 2013.
Article
em En
| MEDLINE
| ID: mdl-23698216
ABSTRACT
Acute generalized exanthematous pustulosis (AGEP) is a significant adverse cutaneous reaction most often induced by drugs and by acute infections. Its clinical hallmark is the sudden onset of multiple, disseminated, non-follicular, sterile pustules on an erythematous background usually arising in intertriginous folds, associated with fever, massive neutrophilia and sometimes eosinophilia. Antitubercular therapy is described as an uncommon cause of AGEP. We report the onset of disseminated non-follicular sterile pustules on an erythematous background in a 68-year-old man receiving a combination of isoniazid, pyrazinamide and rifampicin that may have been the etiologic agents. A thorough history, including a medication history, with clinicopathologic correlation is crucial in patients presenting with acute diffuse pustular lesions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pustulose Exantematosa Aguda Generalizada
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Antituberculosos
Limite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Clin Ter
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Itália