Management strategy for small duodenal carcinoid tumors: does conservative management with close follow-up represent an alternative to endoscopic treatment?
Digestion
; 87(4): 247-53, 2013.
Article
em En
| MEDLINE
| ID: mdl-23751414
ABSTRACT
BACKGROUND/AIMS:
Limited data exist regarding the natural history of duodenal carcinoid tumors and the efficacy of endoscopic treatment.METHODS:
A total of 27 patients with duodenal carcinoid tumors were enrolled. All tumors were located outside the periampullary region and were ≤10 mm in size. 11 patients underwent endoscopic mucosal resection (EMR) and argon plasma coagulation (APC). 13 patients did not undergo any specific procedure for tumor removal and were followed clinically.RESULTS:
Of 13 patients not undergoing treatment, tumors disappeared in 5 cases during follow-up with diagnostic forceps biopsy. Endoscopically visible lesions remained in the last follow-up endoscopy in 8 patients (61.5%). No lymph node or distant metastases or tumor-related deaths occurred during a median follow-up of 37 months. Of 11 cases treated with EMR, tumor-free resection margins were achieved in 10 cases and no local recurrence occurred after treatment. Two perforations occurred during EMR. Of the 3 cases treated with APC, local recurrence occurred in 1 case.CONCLUSIONS:
Given the risks associated with EMR and the likely favorable natural history of small duodenal carcinoid tumors, conservative management with close follow-up may represent a viable alternative to endoscopic treatment, especially in patients with a high risk of perioperative complications.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tumor Carcinoide
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Duodenoscopia
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Neoplasias Duodenais
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Regressão Neoplásica Espontânea
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Digestion
Ano de publicação:
2013
Tipo de documento:
Article