Pd-catalyzed chemoselective Catellani ortho-arylation of iodopyrroles: rapid total synthesis of rhazinal.
J Am Chem Soc
; 135(25): 9318-21, 2013 Jun 26.
Article
em En
| MEDLINE
| ID: mdl-23758183
ABSTRACT
A Pd-catalyzed chemoselective Catellani reaction of iodopyrroles was developed. The rare chemoselectivity between two different aryl halides was realized by optimizing the kinetics of the different steps of this multicomponent process. The new developed method led to the rapid synthesis of rhazinal in a highly efficient manner.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paládio
/
Pirróis
/
Aldeídos
/
Indolizinas
Idioma:
En
Revista:
J Am Chem Soc
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
China