Argyria following the use of silver-coated megaprostheses: no association between the development of local argyria and elevated silver levels.
Bone Joint J
; 95-B(7): 988-92, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23814255
ABSTRACT
The aims of this study were to evaluate the incidence of local argyria in patients with silver-coated megaprostheses and to identify a possible association between argyria and elevated levels of silver both locally and in the blood. Between 2004 and 2011, 32 megaprostheses with silver coatings were implanted in 20 female and 12 male patients following revision arthroplasty for infection or resection of a malignant tumour, and the levels of silver locally in drains and seromas and in the blood were determined. The mean age of the patients was 46 years (10 to 81); one patient died in the immediate post-operative period and was excluded. Seven patients (23%) developed local argyria after a median of 25.7 months (interquartile range 2 to 44.5). Patients with and without local argyria had comparable levels of silver in the blood and aspiration fluids. The length of the implant did not influence the development of local argyria. Patients with clinical evidence of local argyria had no neurological symptoms and no evidence of renal or hepatic failure. Thus, we conclude that the short-term surveillance of blood silver levels in these patients is not required.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Argiria
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Complicações Pós-Operatórias
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Próteses e Implantes
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Prata
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Bone Joint J
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Áustria