Levodopa inhibits habit-learning in Parkinson's disease.
J Neural Transm (Vienna)
; 121(2): 147-51, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-23959161
ABSTRACT
Mixed dopaminergic medication, comprising dopamine agonists and levodopa, may affect habit-learning in patients with Parkinson's disease (PD). However, the specific impact of levodopa on this effect is unknown. We assessed habit-learning in 20 non-demented PD-patients both with and without levodopa. We observed intact habit-learning in PD-patients OFF-medication. In contrast, the administration of 200 mg of levodopa impaired habit-learning. We conclude that potential deficits in habit-learning in PD may be attributed to the intake of levodopa.
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Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Levodopa
/
Ecossistema
/
Deficiências da Aprendizagem
/
Antiparkinsonianos
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Neural Transm (Vienna)
Ano de publicação:
2014
Tipo de documento:
Article