Neurosurgical interventions for patients with nasopharyngeal carcinoma: a single institution experience.
World J Surg Oncol
; 11: 227, 2013 Sep 13.
Article
em En
| MEDLINE
| ID: mdl-24034781
ABSTRACT
BACKGROUND:
Nasopharyngeal carcinoma (NPC) is a frequent head and neck cancer in southern China and Southeast Asia. The majority of NPC patients are managed by radiation oncologists, medical oncologists and head and neck surgeons. Actually, neurosurgical interventions are warranted under specific circumstances. In this article, we described our experience as neurosurgeons in the management of NPC patients.METHODS:
Medical records of NPC patients who received neurosurgical procedure at Sun Yat-sen University Cancer Center were reviewed.RESULTS:
Twenty-seven patients were identified. Among 27 cases, neurosurgical procedures were performed in 18 (66.7%) with radiation-induced temporal necrosis, 2 (7.4%) with radiation-induced sarcoma, 4 (14.8%) with synchronous NPC with primary brain tumors, 2 (7.4%) with recurrent NPC involving skull base, and 1 (3.7%) with metachronous skull eosinophilic granuloma, respectively. The diagnosis is challenging in specific cases and initial misdiagnoses were found in 6 (22.2%) patients.CONCLUSIONS:
For NPC patients with intracranial or skull lesions, the initial diagnosis can be occasionally difficult because of the presence or a history of NPC and related treatment. Unawareness of these entities can result in misdiagnosis and subsequent improper treatment. Neurosurgical interventions are necessary for the diagnosis and treatment for these patients.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Lesões por Radiação
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Sarcoma
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Neoplasias Encefálicas
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Neoplasias Nasofaríngeas
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Procedimentos Neurocirúrgicos
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Recidiva Local de Neoplasia
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
World J Surg Oncol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
China