Ethyl 2-[5-(4-fluoro-phen-yl)pyridin-3-yl]-1-[3-(2-oxopyrrolidin-1-yl)prop-yl]-1H-benzimidazole-5-carboxyl-ate.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 7): o1013-4, 2013.
Article
em En
| MEDLINE
| ID: mdl-24046597
ABSTRACT
In the title compound, C28H27FN4O3·H2O, the benzimidazole ring system is essentially planar with a maximum deviation of 0.028â
(1)â
Å. It makes dihedral angles of 47.59â
(5) and 60.31â
(5)°, respectively, with the pyridine and benzene rings, which make a dihedral angle of 22.58â
(6)° with each other. The pyrrolidine ring shows an envelope conformation with one of the methyl-ene C atoms as the flap. In the crystal, the components are connected into a tape along the b-axis direction through O-Hâ¯O and O-Hâ¯N hydrogen bonds and a π-π inter-action between the pyridine and benzene rings [centroid-centroid distance of 3.685â
(8)â
Å]. The tapes are further linked into layers parallel to the ab plane by C-Hâ¯O and C-Hâ¯F inter-actions.
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Revista:
Acta Crystallogr Sect E Struct Rep Online
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Malásia