[Treatment of severe and uncomplicated falciparum malaria in children in France]. / Traitement du paludisme grave et du paludisme non compliqué à P. falciparum chez l'enfant en France.
Arch Pediatr
; 20(11): 1260-1264, 2013 Nov.
Article
em Fr
| MEDLINE
| ID: mdl-24094758
ABSTRACT
Quinine was the main treatment for malaria between 1630 and the beginning of the XXth century. In the 1940s, the synthesis of chloroquine gave rise to the hope of eliminating this plague. Falciparum resistance to chloroquine, first observed in Asia then in sub-Saharan Africa, lead researchers to discover halofantrine, mefloquine, atovaquone-proguanil and artemisinin combined therapies. There is no ideal treatment for uncomplicated imported malaria in children. Medical teams have to develop a protocol according to available drugs and their personal experience, with a special attention to follow-up at days 3-4 and day 28. From now on, severe malaria must be treated with intravenous artesunate, a more effective therapy than quinine.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Malária Falciparum
Tipo de estudo:
Guideline
Limite:
Child
/
Humans
País/Região como assunto:
Europa
Idioma:
Fr
Revista:
Arch Pediatr
Ano de publicação:
2013
Tipo de documento:
Article