Ca2+ and Ca2+-activated K+ currents in mammalian gastric smooth muscle cells.
Science
; 229(4710): 269-72, 1985 Jul 19.
Article
em En
| MEDLINE
| ID: mdl-2409600
ABSTRACT
Inward movement of calcium through voltage-dependent channels in muscle is thought to initiate the action potential and trigger contraction. Calcium-activated potassium channels carry large outward potassium currents that may be responsible for membrane repolarization. Calcium and calcium-activated potassium currents were identified in enzymatically isolated mammalian gastric myocytes. These currents were blocked by cadmium and nifedipine but were not substantially affected by diltiazem or D600. No evidence for a tetrodotoxin-sensitive sodium current or an inwardly rectifying potassium current was found.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Potássio
/
Estômago
/
Cálcio
/
Canais Iônicos
/
Músculo Liso
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1985
Tipo de documento:
Article