PANADA: protein association network annotation, determination and analysis.
PLoS One
; 8(11): e78383, 2013.
Article
em En
| MEDLINE
| ID: mdl-24265686
ABSTRACT
Increasingly large numbers of proteins require methods for functional annotation. This is typically based on pairwise inference from the homology of either protein sequence or structure. Recently, similarity networks have been presented to leverage both the ability to visualize relationships between proteins and assess the transferability of functional inference. Here we present PANADA, a novel toolkit for the visualization and analysis of protein similarity networks in Cytoscape. Networks can be constructed based on pairwise sequence or structural alignments either on a set of proteins or, alternatively, by database search from a single sequence. The Panada web server, executable for download and examples and extensive help files are available at URL http//protein.bio.unipd.it/panada/.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Software
/
Internet
/
Mapeamento de Interação de Proteínas
/
Anotação de Sequência Molecular
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
PLoS One
Assunto da revista:
CIENCIA
/
MEDICINA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Itália