Personal exposure levels of PAHs in the general population in northern rural area of Jiangsu Province, China.
J Environ Sci Health A Tox Hazard Subst Environ Eng
; 49(3): 281-6, 2014.
Article
em En
| MEDLINE
| ID: mdl-24279619
ABSTRACT
Polycyclic aromatic hydrocarbons (PAHs) are a group of compounds that are produced by incomplete combustion of organic matters. Studies in humans have shown associations between PAHs exposure and development of cancers. Urinary monohydroxy polycyclic aromatic hydrocarbons (OH-PAHs) are a class of PAH metabolites used as biomarkers for estimating human exposure to PAHs. We collected 332 urinary samples from a nonoccupational population in northern rural area of Jiangsu. Levels of 2-hydroxynathalene (2-OHN), 2-hydroxyfluorene (2-OHF) and 1-hydroxypyrene (1-OHP) were measured as biomarkers to assess body PAHs burdens. Three PAH metabolites were detected in more than 80% of urinary samples. After being adjusted with urinary creatinine concentration, the urinary concentrations were determined as 2-OHF > 1-OHP > 2-OHN in terms. The medians of 2-OHN, 2-OHF, 1-OHP for the general population were 1.74, 30.01, 25.24 µmoL/moL creatinine, respectively. The results demonstrated that nonoccupational populations in northern rural area of Jiangsu were exposed to extremely high PAHs. The urinary concentration (median and geometric mean) of 2-OHN,2-OHF,1-OHP in males (1.90, 0.37 ± 0.46; 34.90, 1.53 ± 0.41; 27.84, 1.52 ± 0.29 µmoL/moL creatinine, respectively) was slightly higher than in females (1.56, 0.32 ± 0.42; 29.60, 1.48 ± 0.40; 23.13, 1.49 ± 0.32 µmoL/moL creatinine, respectively). However, only 2-OHN was different significantly between males and females.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hidrocarbonetos Policíclicos Aromáticos
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Biomarcadores
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Exposição Ambiental
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Environ Sci Health A Tox Hazard Subst Environ Eng
Assunto da revista:
TOXICOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article