Complementary stereochemical outcomes in proline-based self-regenerations of stereocenters.
Org Lett
; 16(2): 432-5, 2014 Jan 17.
Article
em En
| MEDLINE
| ID: mdl-24377839
ABSTRACT
Stereoselective alkylations of proline-based amino amides are described, where high levels of either a cis or trans configuration can be attained simply by the choice of the aminal group. Isobutryaldehyde-derived aminals provide the cis configuration, while 1-naphthaldehyde-derived aminals engender the complementary trans configuration.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Prolina
/
Amidas
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Estados Unidos