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BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis.
Tang, Maggie K S; Kwong, Ava; Tam, Kar-Fai; Cheung, Annie N Y; Ngan, Hextan Y S; Xia, Weiliang; Wong, Alice S T.
Afiliação
  • Tang MK; School of Biological Sciences, University of Hong Kong, Pokfulam Road, Hong Kong.
  • Kwong A; Department of Surgery, University of Hong Kong, Pokfulam Road, Hong Kong; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong.
  • Tam KF; Department of Obstetrics and Gynecology, University of Hong Kong, Pokfulam Road, Hong Kong.
  • Cheung AN; Department of Pathology, University of Hong Kong, Pokfulam Road, Hong Kong.
  • Ngan HY; Department of Obstetrics and Gynecology, University of Hong Kong, Pokfulam Road, Hong Kong.
  • Xia W; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China; Clinical Stem Cell Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Wong AS; School of Biological Sciences, University of Hong Kong, Pokfulam Road, Hong Kong. Electronic address: awong1@hku.hk.
Cancer Lett ; 346(1): 139-47, 2014 Apr 28.
Article em En | MEDLINE | ID: mdl-24378767

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Autofagia / Neoplasias da Mama / Proteína BRCA1 Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Hong Kong

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Autofagia / Neoplasias da Mama / Proteína BRCA1 Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Hong Kong