Burden of encephalitis-associated hospitalizations in the United States, 1998-2010.
Neurology
; 82(5): 443-51, 2014 Feb 04.
Article
em En
| MEDLINE
| ID: mdl-24384647
ABSTRACT
OBJECTIVE:
To estimate the burden of encephalitis-associated hospitalizations in the United States for 1998-2010.METHODS:
Using the Nationwide Inpatient Sample, a nationally representative database of hospitalizations, estimated numbers and rates of encephalitis-associated hospitalizations for 1998-2010 were calculated. Etiology and outcome of encephalitis-associated hospitalizations were examined, as well as accompanying diagnoses listed along with encephalitis on the discharge records. Total hospital charges (in 2010 US dollars) were assessed.RESULTS:
An estimated 263,352 (standard error 3,017) encephalitis-associated hospitalizations occurred in the United States during 1998-2010, which corresponds to an average of 20,258 (standard error 232) encephalitis-associated hospitalizations per year. A fatal outcome occurred in 5.8% (95% confidence interval [CI] 5.6%-6.0%) of all encephalitis-associated hospitalizations and in 10.1% (95% CI 9.2%-11.2%) and 17.1% (95% CI 14.6%-20.0%) of encephalitis-associated hospitalizations in which a code for HIV or a tissue or organ transplant was listed, respectively. The proportion of encephalitis-associated hospitalizations in which an etiology for encephalitis was specified was 50.3% (95% CI 49.6%-51.0%) and that for which the etiology was unspecified was 49.7% (95% CI 49.0%-50.4%). Total charges for encephalitis-associated hospitalizations in 2010 were an estimated $2.0 billion.CONCLUSIONS:
Encephalitis remains a major public health concern in the United States. Among the large number of encephalitis-associated hospitalizations for which an etiology is not reported may be novel infectious and noninfectious forms of encephalitis. Associated conditions such as HIV or transplantation increase the risk of a fatal outcome from an encephalitis-associated hospitalization and should be monitored.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Custos de Cuidados de Saúde
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Efeitos Psicossociais da Doença
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Encefalite
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Hospitalização
Tipo de estudo:
Diagnostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Middle aged
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Neurology
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Moldávia