Cholera epidemic associated with consumption of unsafe drinking water and street-vended water--Eastern Freetown, Sierra Leone, 2012.
Am J Trop Med Hyg
; 90(3): 518-23, 2014 Mar.
Article
em En
| MEDLINE
| ID: mdl-24470563
ABSTRACT
During 2012, Sierra Leone experienced a cholera epidemic with 22,815 reported cases and 296 deaths. We conducted a matched case-control study to assess risk factors, enrolling 49 cases and 98 controls. Stool specimens were analyzed by culture, polymerase chain reaction (PCR), and pulsed-field gel electrophoresis (PFGE). Conditional logistic regression found that consuming unsafe water (matched odds ratio [mOR] 3.4; 95% confidence interval [CI] 1.1, 11.0), street-vended water (mOR 9.4; 95% CI 2.0, 43.7), and crab (mOR 3.3; 95% CI 1.03, 10.6) were significant risk factors for cholera infection. Of 30 stool specimens, 13 (43%) showed PCR evidence of toxigenic Vibrio cholerae O1. Six specimens yielded isolates of V. cholerae O1, El Tor; PFGE identified a pattern previously observed in seven countries. We recommended ensuring the quality of improved water sources, promoting household chlorination, and educating street vendors on water handling practices.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Frutos do Mar
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Vibrio cholerae
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Água Potável
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Cólera
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Braquiúros
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Epidemias
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Animals
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Child
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Child, preschool
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Africa
Idioma:
En
Revista:
Am J Trop Med Hyg
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Bangladesh