Antifungal ether diglycosides from Matayba guianensis Aublet.
Bioorg Med Chem Lett
; 24(5): 1414-6, 2014 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-24485783
ABSTRACT
Since the 1960s, fungal infections have become a major worldwide public health problem. Antifungal treatments have many limitations, such as toxicity and resistance. Matayba guianensis Aublet (Sapindaceae) was chemically investigated as part of our ongoing search for lead molecules against fungi in the Brazilian Cerrado biome. The ethanolic extract of M. guianensis root bark revealed the presence of two previously unreported ether diglycosides matayoside E (1) and F (2) with anti Candida activity, along with two known compounds cupanioside (3) and stigmasterol (4).
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sapindaceae
/
Glicosídeos
/
Antifúngicos
Limite:
Humans
Idioma:
En
Revista:
Bioorg Med Chem Lett
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Brasil