Quantitative assessment of myocardial perfusion using time-density curve analysis after elective percutaneous coronary intervention.
J Invasive Cardiol
; 26(2): 60-3, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-24486662
ABSTRACT
UNLABELLED The aim of this study was to assess myocardial blush (MB) using a novel software algorithm that quantifies time-density curves (TDC) after percutaneous coronary intervention (PCI). METHODS:
Thirty-two patients referred for elective PCI were enrolled. TDC curves were generated and mean maximal myocardial contrast density (Dmax) was calculated from 5 regions of interest in the PCI territory. Dmax was normalized to contrast injected in the proximal coronary artery (DI).RESULTS:
Mean DI significantly increased after PCI in all subjects. Dmax correlated directly with subjective grading of Thrombolysis in Myocardial Infarction (TIMI) myocardial blush (R=0.47; P<.01). In 7 subjects referred for PCI of a chronic total occlusion (CTO), mean DI remained increased after PCI. Mean DI was lower in CTO versus non-CTO subjects; however, fold-improvement was higher after PCI of CTO lesions.CONCLUSION:
Quantifying MB using TDC analysis is feasible and correlates with subjective MB grading. The clinical utility of MB quantitation after PCI requires further study.
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Base de dados:
MEDLINE
Assunto principal:
Fluxo Sanguíneo Regional
/
Algoritmos
/
Vasos Coronários
/
Estenose Coronária
/
Imagem de Perfusão do Miocárdio
/
Intervenção Coronária Percutânea
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Invasive Cardiol
Assunto da revista:
CARDIOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article