Dual redox and thermoresponsive double hydrophilic block copolymers with tunable thermoresponsive properties and self-assembly behavior.
Macromol Rapid Commun
; 35(7): 752-7, 2014 Apr.
Article
em En
| MEDLINE
| ID: mdl-24497107
ABSTRACT
The synthesis, tunable thermoresponsive properties, and self-assembly of dual redox and thermoresponsive double hydrophilic block copolymers having pendant disulfide linkages (DHBCss) are reported. Well-defined DHBCss composed of a hydrophilic poly(ethylene oxide) block and a dual thermo- and reduction-responsive random copolymer block containing pendant disulfide linkages are synthesized by atom transfer radical polymerization. Their lower critical solution temperature (LCST) transitions are adjusted through modulating pendant hydrophobic-hydrophilic balance with disulfide-thiol-sulfide chemistry. Further, these DHBCss derivatives are converted to disulfide-crosslinked nanogels at temperatures above LCST through temperature-driven self-assembly and in situ disulfide crosslinking. They exhibit enhanced colloidal stability and further reduction-responsive degradability, thus demonstrating versatility of dual thermo- and reduction-responsive smart materials.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Temperatura
/
Interações Hidrofóbicas e Hidrofílicas
Idioma:
En
Revista:
Macromol Rapid Commun
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Canadá