Nidovirus papain-like proteases: multifunctional enzymes with protease, deubiquitinating and deISGylating activities.

Mielech, Anna M; Chen, Yafang; Mesecar, Andrew D; Baker, Susan C

Mielech, Anna M; Chen, Yafang; Mesecar, Andrew D; Baker, Susan C.

Afiliação

Mielech AM; Department of Microbiology and Immunology, Loyola University Chicago, Stritch School of Medicine, 2160 S. First Avenue, Maywood, IL 60153, United States.
Chen Y; Department of Biological Sciences, Purdue University, Hockmeyer Hall of Structural Biology, 240 S. Martin Jischke Drive, West Lafayette, IN 47907, United States.
Mesecar AD; Department of Biological Sciences, Purdue University, Hockmeyer Hall of Structural Biology, 240 S. Martin Jischke Drive, West Lafayette, IN 47907, United States.
Baker SC; Department of Microbiology and Immunology, Loyola University Chicago, Stritch School of Medicine, 2160 S. First Avenue, Maywood, IL 60153, United States. Electronic address: sbaker1@lumc.edu.

Virus Res ; 194: 184-90, 2014 Dec 19.

Article em En | MEDLINE | ID: mdl-24512893

Assuntos

Enzimas Multifuncionais/metabolismo; Nidovirales/enzimologia; Peptídeo Hidrolases/metabolismo; Proteases Específicas de Ubiquitina/metabolismo

Palavras-chave

Arterivirus; Coronavirus; DeISGylating activity; Deubiquitinating enzyme; MERS-CoV; Papain-like protease

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Nidovirales / Enzimas Multifuncionais Idioma: En Revista: Virus Res Assunto da revista: VIROLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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