Doripenem, gentamicin, and colistin, alone and in combinations, against gentamicin-susceptible, KPC-producing Klebsiella pneumoniae strains with various ompK36 genotypes.

Clancy, Cornelius J; Hao, Binghua; Shields, Ryan K; Chen, Liang; Perlin, David S; Kreiswirth, Barry N; Nguyen, M Hong

Clancy, Cornelius J; Hao, Binghua; Shields, Ryan K; Chen, Liang; Perlin, David S; Kreiswirth, Barry N; Nguyen, M Hong.

Afiliação

Clancy CJ; University of Pittsburgh, Pittsburgh, Pennsylvania, USA XDR Pathogen Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Pittsburgh VA Healthcare System, Pittsburgh, Pennsylvania, USA.
Hao B; University of Pittsburgh, Pittsburgh, Pennsylvania, USA XDR Pathogen Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Shields RK; University of Pittsburgh, Pittsburgh, Pennsylvania, USA XDR Pathogen Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Chen L; Public Health Research Institute, New Jersey Medical School-University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
Perlin DS; Public Health Research Institute, New Jersey Medical School-University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
Kreiswirth BN; Public Health Research Institute, New Jersey Medical School-University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
Nguyen MH; University of Pittsburgh, Pittsburgh, Pennsylvania, USA XDR Pathogen Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA mhn5@pitt.edu.

Antimicrob Agents Chemother ; 58(6): 3521-5, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24566172

Assuntos

Antibacterianos/farmacologia; Carbapenêmicos/farmacologia; Colistina/farmacologia; Gentamicinas/farmacologia; Klebsiella pneumoniae/efeitos dos fármacos; beta-Lactamases/genética; Algoritmos; Ácido Aspártico; Proteínas de Bactérias/genética; Doripenem; Quimioterapia Combinada; Genótipo; Glicina; Klebsiella pneumoniae/enzimologia; Klebsiella pneumoniae/genética; Testes de Sensibilidade Microbiana; Mutagênese Insercional; Porinas/genética; beta-Lactamases/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Gentamicinas / Carbapenêmicos / Colistina / Klebsiella pneumoniae / Antibacterianos Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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