Evaluation of the Macula, Retinal Nerve Fiber Layer, and Choroid Thickness in Women With Polycystic Ovary Syndrome Using Spectral-Domain Optical Coherence Tomography.

ABSTRACT

This study aimed to investigate the macular, retinal nerve fiber layer (RNFL), and choroid thickness alterations using spectral-domain optical coherence tomography in women with polycystic ovary syndrome (PCOS) and to compare them with healthy reproductive-age women volunteers. Study group consisted of 64 patients with PCOS and control group consisted of 60 healthy volunteers. There was a statistically significant difference between PCOS and control groups for choroid thickness (P < .001). Fovea center thickness and temporal inner macula were significantly thinner in the PCOS group than those in the healthy control group (P = .009 and P = .033, respectively). Contrary to these findings, nasal outer macula (NOM) and temporal outer macula (TOM) were statistically thicker in the PCOS group than those in the control group (P = .001 and P < .001, respectively). Increased choroid thickness and RNFL may lead to increase in both retinal volume and retinal thickness in the peripheral side of the retina. Therefore, NOM and TOM region can be accepted sensitive areas in patients with PCOS.