A switchable [2]rotaxane asymmetric organocatalyst that utilizes an acyclic chiral secondary amine.
J Am Chem Soc
; 136(13): 4905-8, 2014 Apr 02.
Article
em En
| MEDLINE
| ID: mdl-24649824
ABSTRACT
A rotaxane-based switchable asymmetric organocatalyst has been synthesized in which the change of the position of the macrocycle reveals or conceals an acyclic, yet still highly effective, chiral organocatalytic group. This allows control over both the rate and stereochemical outcome of a catalyzed asymmetric Michael addition.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Rotaxanos
/
Aminas
Idioma:
En
Revista:
J Am Chem Soc
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Reino Unido