Bioretrosynthetic construction of a didanosine biosynthetic pathway.

Birmingham, William R; Starbird, Chrystal A; Panosian, Timothy D; Nannemann, David P; Iverson, T M; Bachmann, Brian O

Birmingham, William R; Starbird, Chrystal A; Panosian, Timothy D; Nannemann, David P; Iverson, T M; Bachmann, Brian O.

Afiliação

Birmingham WR; 1] Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, USA. [2].
Starbird CA; Chemical and Physical Biology Program, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Panosian TD; 1] Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. [2].
Nannemann DP; 1] Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA. [2].
Iverson TM; 1] Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, USA. [2] Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Bachmann BO; 1] Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, USA. [2] Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA.

Nat Chem Biol ; 10(5): 392-9, 2014 May.

Article em En | MEDLINE | ID: mdl-24657930

Assuntos

Didanosina/metabolismo; Biocatálise; Evolução Molecular Direcionada; Enzimas/metabolismo; Modelos Moleculares

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Didanosina Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article

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