Multidimensional reaction screening for photochemical transformations as a tool for discovering new chemotypes.
J Org Chem
; 79(9): 3838-46, 2014 May 02.
Article
em En
| MEDLINE
| ID: mdl-24697145
ABSTRACT
We have developed an automated photochemical microfluidics platform that integrates a 1 kW high-pressure Hg vapor lamp and allows for analytical pulse flow or preparative continuous flow reactions. Herein, we will discuss the use of this platform toward the discovery of new chemotypes through multidimensional reaction screening. We will highlight the ability to discretely control wavelengths with optical filters, allowing for control of reaction outcomes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Compostos Orgânicos
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Estados Unidos