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Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
Guthridge, Joel M; Lu, Rufei; Sun, Harry; Sun, Celi; Wiley, Graham B; Dominguez, Nicolas; Macwana, Susan R; Lessard, Christopher J; Kim-Howard, Xana; Cobb, Beth L; Kaufman, Kenneth M; Kelly, Jennifer A; Langefeld, Carl D; Adler, Adam J; Harley, Isaac T W; Merrill, Joan T; Gilkeson, Gary S; Kamen, Diane L; Niewold, Timothy B; Brown, Elizabeth E; Edberg, Jeffery C; Petri, Michelle A; Ramsey-Goldman, Rosalind; Reveille, John D; Vilá, Luis M; Kimberly, Robert P; Freedman, Barry I; Stevens, Anne M; Boackle, Susan A; Criswell, Lindsey A; Vyse, Tim J; Behrens, Timothy W; Jacob, Chaim O; Alarcón-Riquelme, Marta E; Sivils, Kathy L; Choi, Jiyoung; Joo, Young Bin; Bang, So-Young; Lee, Hye-Soon; Bae, Sang-Cheol; Shen, Nan; Qian, Xiaoxia; Tsao, Betty P; Scofield, R Hal; Harley, John B; Webb, Carol F; Wakeland, Edward K; James, Judith A; Nath, Swapan K; Graham, Robert R.
Afiliação
  • Guthridge JM; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: guthridgej@omrf.org.
  • Lu R; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Sun H; Immune and Tissue Growth and Repair and Human Genetics Department, Genentech, South San Francisco, CA 94080, USA.
  • Sun C; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Wiley GB; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Dominguez N; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Macwana SR; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Lessard CJ; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Kim-Howard X; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Cobb BL; Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Kaufman KM; Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA.
  • Kelly JA; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Langefeld CD; Department of Biostatistical Sciences, Wake Forest University, Winston-Salem, NC 27106, USA.
  • Adler AJ; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Harley IT; Division of Molecular Immunology and Graduate Program in Immunobiology, Cincinnati Children's Hospital Research Foundation, Cincinnati, OH 45229, USA.
  • Merrill JT; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Gilkeson GS; Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Kamen DL; Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Niewold TB; Division of Rheumatology and Department of Immunology, Mayo Clinic, Rochester, MN 55902, USA.
  • Brown EE; Department of Epidemiology, University of Alabama-Birmingham, Birmingham, AL 35294, USA; Department of Medicine, University of Alabama-Birmingham, Birmingham, AL 35294, USA.
  • Edberg JC; Division of Clinical Immunology and Rheumatology, University of Alabama-Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Petri MA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Ramsey-Goldman R; Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Reveille JD; Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, TX.77030, USA.
  • Vilá LM; Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan 00921, Puerto Rico.
  • Kimberly RP; Division of Clinical Immunology and Rheumatology, University of Alabama-Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Freedman BI; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27106, USA.
  • Stevens AM; Division of Rheumatology, Department of Pediatrics, University of Washington Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101, USA.
  • Boackle SA; Division of Rheumatology, University of Colorado Denver, Aurora, CO 80045, USA.
  • Criswell LA; Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, San Francisco, CA 94143, USA.
  • Vyse TJ; Division of Medicine, Imperial College of London, London SW7 2AZ, UK.
  • Behrens TW; Immune and Tissue Growth and Repair and Human Genetics Department, Genentech, South San Francisco, CA 94080, USA.
  • Jacob CO; Department of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
  • Alarcón-Riquelme ME; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Centro de Genómica e Investigaciones Oncológicas (GENYO). Pfizer-Universidad de Granada-Junta de Andalucía, Granada 18016, Spain.
  • Sivils KL; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Choi J; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-791, Korea.
  • Joo YB; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-791, Korea.
  • Bang SY; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-791, Korea.
  • Lee HS; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-791, Korea.
  • Bae SC; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-791, Korea.
  • Shen N; Molecular Rheumatology Laboratory, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • Qian X; Molecular Rheumatology Laboratory, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • Tsao BP; Department of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
  • Scofield RH; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73105, USA; United States Department of Veterans Affairs Medical Center, Oklahoma City, OK 73105, US
  • Harley JB; Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA.
  • Webb CF; Immunobiology and Cancer Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Cell Biology and Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Wakeland EK; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA.
  • James JA; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, O
  • Nath SK; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Graham RR; Immune and Tissue Growth and Repair and Human Genetics Department, Genentech, South San Francisco, CA 94080, USA.
Am J Hum Genet ; 94(4): 586-98, 2014 Apr 03.
Article em En | MEDLINE | ID: mdl-24702955
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regiões Promotoras Genéticas / Quinases da Família src / Lúpus Eritematoso Sistêmico Tipo de estudo: Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Am J Hum Genet Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regiões Promotoras Genéticas / Quinases da Família src / Lúpus Eritematoso Sistêmico Tipo de estudo: Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Am J Hum Genet Ano de publicação: 2014 Tipo de documento: Article