[Primary selective IgM deficiency--forgotten primary immunodeficiency?]. / Izolowany niedobór IgM--ignorowany pierwotny niedobór odpornosci?
Przegl Lek
; 70(12): 1056-7, 2013.
Article
em Pl
| MEDLINE
| ID: mdl-24720127
ABSTRACT
Immunoglobulin M is a pentamer found in the intravascular compartment and on the surface of B lymphocytes. It is the antibody isotype produced initially in the immune response, and the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. Decreased levels of IgM have been associated with autoimmune disease, several primary immunodeficiency but exist also as selected primary immunodeficiency.
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Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Imunoglobulina M
/
Disgamaglobulinemia
/
Síndromes de Imunodeficiência
Limite:
Humans
Idioma:
Pl
Revista:
Przegl Lek
Ano de publicação:
2013
Tipo de documento:
Article