Haploinsufficiency of an RB-E2F1-Condensin II complex leads to aberrant replication and aneuploidy.

Coschi, Courtney H; Ishak, Charles A; Gallo, David; Marshall, Aren; Talluri, Srikanth; Wang, Jianxin; Cecchini, Matthew J; Martens, Alison L; Percy, Vanessa; Welch, Ian; Boutros, Paul C; Brown, Grant W; Dick, Frederick A

Coschi, Courtney H; Ishak, Charles A; Gallo, David; Marshall, Aren; Talluri, Srikanth; Wang, Jianxin; Cecchini, Matthew J; Martens, Alison L; Percy, Vanessa; Welch, Ian; Boutros, Paul C; Brown, Grant W; Dick, Frederick A.

Afiliação

Coschi CH; Authors' Affiliations:London Regional Cancer Program; Department of Biochemistry, and.
Ishak CA; Authors' Affiliations:London Regional Cancer Program; Department of Biochemistry, and.
Gallo D; Biochemistry, Donnelly Centre, University of Toronto; and.
Marshall A; Authors' Affiliations:London Regional Cancer Program; Department of Biochemistry, and.
Talluri S; Authors' Affiliations:London Regional Cancer Program; Department of Biochemistry, and.
Wang J; Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Cecchini MJ; Authors' Affiliations:London Regional Cancer Program; Department of Biochemistry, and.
Martens AL; Authors' Affiliations:London Regional Cancer Program; Department of Biochemistry, and.
Percy V; Authors' Affiliations:London Regional Cancer Program;
Welch I; Veterinary Services, Western University, London; Departments of.
Boutros PC; Medical Biophysics, and Pharmacology and Toxicology, Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Brown GW; Biochemistry, Donnelly Centre, University of Toronto; and.
Dick FA; Authors' Affiliations:London Regional Cancer Program; Children's Health Research Institute; Department of Biochemistry, and fdick@uwo.ca.

Cancer Discov ; 4(7): 840-53, 2014 Jul.

Article em En | MEDLINE | ID: mdl-24740996

Assuntos

Adenosina Trifosfatases/genética; Aneuploidia; Replicação do DNA; Proteínas de Ligação a DNA/genética; Fator de Transcrição E2F1/genética; Complexos Multiproteicos/genética; Neoplasias/genética; Proteína do Retinoblastoma/genética; Adenosina Trifosfatases/metabolismo; Animais; Linhagem Celular Tumoral; Células Cultivadas; Centrômero/metabolismo; Variações do Número de Cópias de DNA; Proteínas de Ligação a DNA/metabolismo; Fator de Transcrição E2F1/metabolismo; Embrião de Mamíferos; Fibroblastos/metabolismo; Haploinsuficiência; Humanos; Camundongos; Complexos Multiproteicos/metabolismo; Proteína do Retinoblastoma/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína do Retinoblastoma / Adenosina Trifosfatases / Complexos Multiproteicos / Proteínas de Ligação a DNA / Replicação do DNA / Fator de Transcrição E2F1 / Aneuploidia / Neoplasias Limite: Animals / Humans Idioma: En Revista: Cancer Discov Ano de publicação: 2014 Tipo de documento: Article

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