The prevalence and determinants of short stature in HIV-infected children.
J Int Assoc Provid AIDS Care
; 13(6): 529-33, 2014.
Article
em En
| MEDLINE
| ID: mdl-24752886
ABSTRACT
BACKGROUND:
Children with HIV infection are often reported to be short. The aim of this study was to assess the prevalence of HIV-associated short stature in HIV endemic setting.METHODS:
Data were obtained by retrospective review of the electronic medical records. Patients were grouped into various clinical categories. For each category, the proportion of patients with height-for-age Z score of less than -2 standard deviation [SD] and of less than -3 SD was determined.RESULTS:
The prevalence of short stature (less than -2 SD) was 28.4%. Severe short stature (less than -3 SD) is more likely with percentage of CD4 <15% (odds ratio [OR] 3.30, confidence interval [CI] 1.51-7.09, P = .002) and with males (OR 1.49, CI 1.19-1.87, P = .001). Severe short stature is more likely with viral load >400 copies/mL (OR 2.64, CI 1.27-5.38, P = .008) and poor adherence (<95%; OR 1.72, CI 1.03-2.05, P = .037).CONCLUSION:
In Botswana, short stature affects a quarter of HIV-infected children and severe short stature is associated with poor adherence to antiretroviral treatment, severe immunosuppression, and virologic failure.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estatura
/
Infecções por HIV
/
Transtornos do Crescimento
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
Africa
Idioma:
En
Revista:
J Int Assoc Provid AIDS Care
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Botsuana